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A Rare Case of Hodgkin's Lymphoma in Accessory Spleen

Odianosen Obadan, Raymond Pastore, Deborah Schron and Obiora Anyoku

Accessory spleen (AS) is a congenital focus of healthy splenic tissue that is separated from the main body of the spleen. It is a frequently normal variant that is found in up to 30% of cases at autopsy examination. According to literature, it is usually an incidental finding because it is assymptomatic. It might even be confused as a lymph node on CT scan. It is thought that most accessory spleens are tiny and incapable of pathogenic activity. Hodgkin lymphoma (HL) exclusively in the accessory spleen has been seldom reported in the literature. We report a rare case of a HIV positive man with Classic Hodgkin lymphoma in accessory spleen, with B symptoms, positive markers and positive Epstein Barr Virus (EBV) LMP. He showed symptomatic and laboratory improvement on antiretroviral therapy and was referred for ABVD with outpatient follow up.