欧洲实验生物学杂志 开放获取

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Antioxidant and antimicrobial activity of individual catechin molecules: A comparative study between gallated and epimerized catechin molecules

K.M. Maria John, J. Rajesh, A.K.A. Mandal and Sampath Natarajan

Protection of DNA samples against free radical damage was found to elevate with Gallocatechin gallate (GCG) followed by epigallo catechin (EGC). Epicatechin gallate and (+) catechin exhibited lower quantum of free radical scavenging activity. It is interesting to note that higher concentration of individual catechin molecules registered concurrent protection of DNA from free radical damage. Results showed that the epimerized form of gallocatechin gallate had high antagonistic effect against both the tested strains followed by epigallo catechin while, catechin gallate and (+) catechin recorded lower activity against microbes. Among the phenolic acids pyrogallic acid possessed high antimicrobial activity.