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Comparison Different Automated Systems for Detection of Penicillinase in Staphylococcus Aureus

Kai-sen Chen, Shirong Lin, Pei-qun Li, Xia Dong, Dong Luo and Wei Zhang

The accuracy of Vitek 2, WalkAway 40, and DL-96 systems for susceptibility testing of penicillin against 547 S. aureus was evaluated using broth micro dilution. BlaZ gene was taken as gold standard to predict penicillinase-producing or not. Overall, there are no very major error in Vitek 2, one in WalkAway 40 and seven in DL-96. No major errors and 59 minor errors were noted in this study. The results showed that Vitek 2 had more reliable rate to predict penicillinaseproducing S. aureus.

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