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Epigenetics and Orthopedics

Recep Ozturk, Bayram Taskın, Omer Faruk Ates and Osman İnan4

Especially in recent years, there are many cases in which the known genetic analyses are not enough and that can be explained with the mechanism beyond genetics, which are studied under the titles of epigenetic regulation. ‘Epigenetic’ term refers to activity of the hereditary phenotypic changes that are not resulted in changes in DNA sequence. The objective of this study is to provide information about the epigenetic mechanisms and some epigenetic disorders that may also involve orthopedic signs and symptoms.

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