美国药物输送和治疗杂志 开放获取

抽象的

Nano Aerogels an Aerosolised Gel Therapy

P.R.Bageedhar rao* Y.prasanth

Administration of medications via aerosolization with gels is potentially an ideal strategy to treat airway diseases. This delivery method ensures high concentrations of the medication in the targeted tissues, the airways, with generally lower systemic absorption and systemic adverse effects. Aerosolized antibiotics have been tested as treatment for bacterial infections and viral infections in patients with cystic fibrosis (CF), non-CF bronchiectasis (NCFB),pneumonia,Coronary Obstructive Pulmonary Disorder(COPD) and ventilator-associated pneumonia (VAP). The most successful application is the treatment of infections in patients with CF. It has been hypothesized that similar success would be seen in NCFB . This review summarizes the available evidence supporting the use of aerosolized antibiotics in many bacterial and viral infections to potentiate immediate release of drug at targeted site and also may shows effective results on corona virus in futuristic view .