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Non-oliguric Renal Failure with Nephromegaly as the presenting Manifestation of Acute Lymphoblastic Leukemia in a Young Adult

Rushi Deshpande, Ashwin Patil, Sudhiranjan Dash, Ganpati Bhat, *Shaurya Mehta

Renal failure as the initial presenting manifestation of acute lymphoblastic leukemia (ALL) is uncommon. In Acute leukemia, commonly occurring renal complications are due to leukemic infiltration of the kidneys, treatment-related side effects such as tumor lysis syndrome, nephrotoxic drugs, sepsis. We have presented a case of 25 year female presenting with non-oliguric Acute kidney injury of unknown etiology presenting with raised creatinine and abdominal pain without any other predisposing factor. On thorough investigation, she was diagnosed to have Acute Lymphoblastic Leukemia. The clinical lesson to be learnt from this case is that a complete detailed clinical examination and laboratory work up must be done before labelling AKI as unknown etiology.