Journal of Neuro-Oncology and Neuroscience 开放获取

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Paraneoplastic Autoimmune Limbic Encephalitis Associated with an Atypical Carcinoid Tumor of the Lung

Emma Marull Paretas, Claudio De Vito, Francoise Bernasconi, Sabina Catalano, Maria-Isabel Vargas, Frederic Assal, Patrice H Lalive, Claire Bridel

We report the case of a woman with a history of atypical carcinoid tumor of the lung that developed a rapidly progressive memory impairment. Clinical presentation as well as brain MRI, cerebrospinal fluid and laboratory testing led to the diagnosis of seronegative paraneoplastic autoimmune limbic encephalitis. To the best of our knowledge, this is the first case in literature of such association. This case also highlights an exceptionally favorable outcome, both clinically and radiologically, after immunosuppression and tumor removal.