P.P.A. Ikokoh, H.O. Onigbanjo, O. Adedirin, J.O. Akolade, Uzo Amuzie and A. Fagbohun
Complexes of copper (1) thiourea and silver (1) thiourea were synthesized from copper sulphate, silver nitrate and thiourea for the purpose of investigating its antimicrobial activities. The antimicrobial potentials of these complexes were tested with Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, Bacillus subtilis and Candida albicans. The minimum inhibitory concentration was determined for the metal complexes which ranges from 24.5-34mm. While that of the antibiotics ranges from 13.5-34.5mm. The complexes tested were effective against these groups of microorganism. The compounds showed a promising antimicrobial activity when compared with three antibiotics standards: Chloramphenicol, Amoxicillin and Nystatin used as positive control. These complexes have shown potential of being broad spectrum antibacterial and antifungal in nature.
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